4-甲氧基-1,2-二氢萘

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The compound 22 (345 mg, 1 mmol) was converted to the enol ether with 1-methoxy-3,4-dihydronaphthalene (801 mg, 10 mmol) in the same manner as the example 41 to give the compound 51 (226 mg, 47.8%). Mp 99-102° C. PMR (CDCl3 -0.1% d5 -Py): δH1.26 (6 H, d, J 7 Hz, (CH3)2C), 2.73 (2 H, t, J 7.8 Hz, =-CH2), 3.27 (2 H, t, J 6.2 Hz, CH2 -Im), 3.11 (1 H, m, (CH3)2CH), 3.54 (3 H, s, NCH3), 4.22 (2 H, t, J 6.2 Hz, OCH2), 5.04 (1 H, t, J 6.4 Hz, =CH), 6.79 (2 H, d, J 1.6 Hz, arom-H), 7.4-7.0 (5 H, m, arom-H) IR(KBr)cm-1 : 3434, 3060, 1636, 1566, 1252, 1099. Elementary analysis (for C25H26N2Ocl2S) Calcd. : C, 63.42% H, 5.53% N, 5.92% S, 6.77% Cl, 14.98% Found: C, 64.13% H, 5.74% N, 5.74% S, 6.62% Cl, 14.11%

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The compound 22 (345 mg, 1 mmol) was converted to the enol ether with 1-methoxy-3,4-dihydronaphthalene (801 mg, 10 mmol) in the same manner as the example 41 to give the compound 51 (226 mg, 47.8%). Mp 99-102° C. PMR (CDCl3 -0.1% d5 -Py): δH1.26 (6 H, d, J 7 Hz, (CH3)2C), 2.73 (2 H, t, J 7.8 Hz, =-CH2), 3.27 (2 H, t, J 6.2 Hz, CH2 -Im), 3.11 (1 H, m, (CH3)2CH), 3.54 (3 H, s, NCH3), 4.22 (2 H, t, J 6.2 Hz, OCH2), 5.04 (1 H, t, J 6.4 Hz, =CH), 6.79 (2 H, d, J 1.6 Hz, arom-H), 7.4-7.0 (5 H, m, arom-H) IR(KBr)cm-1 : 3434, 3060, 1636, 1566, 1252, 1099. Elementary analysis (for C25H26N2Ocl2S) Calcd. : C, 63.42% H, 5.53% N, 5.92% S, 6.77% Cl, 14.98% Found: C, 64.13% H, 5.74% N, 5.74% S, 6.62% Cl, 14.11%